IndraLab

Statements

USP8 inhibits KDR. 3 / 4

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"VEGF-A-stimulated VEGFR2 signal transduction is perturbed by USP8 depletion."

26459808

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"USP8 depletion can significantly increase the retention of VEGFR2 in early endosomes and reduce its recycling to the plasma membrane."

36998063

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"Ubiquitin isopeptidase USP8 [32] and ER-resident ubiquitin E3 ligase RNF121 mediate degradation of immature VEGFR2 [33]."

36928770

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP8 inhibits KDR. 3 / 4

INDRA sources:

Databases

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