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ATP bound to its inhibits CASP1. 1 / 1

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"Inhibition of the P2x7 pathway in vitro restores the potential of CD34 + HPC differentiation into T cells in INR patients, further confirming this view.37 The binding of ATP with its receptor, P2x7, induces the formation of inflammatory bodies, activates the caspase-1 signaling pathway, and promotes the secretion of the proinflammatory cytokines IL-1beta and IL-18, thus inducing host cell apoptosis and pyroptosis.38 Another study by Guo etal."

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ATP bound to its inhibits CASP1. 1 / 1

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