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CACNA1S activates sodium atom. 2 / 2
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"Familial forms of hypoPP are caused by SCN4A (20%) and CACNA1S (60%) mutations of positively charged residues in the channel voltage sensor that create an aberrant permeation pathway for H + or Na + ions, resulting in depolarizing cation leak currents named gating pore currents."
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"Because of the higher frequency of attacks in SPP patients with mutations compared with SPP patients without mutation, we hypothesize that the mutations in CACNA1S and SCN4A increase the susceptibilit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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