IndraLab

Statements

USP17L2 activates SNAI1. 3 / 3
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eidos
"Inhibition of USP17 promotes SNAI1 degradation , thereby suppressing breast cancer invasion and metastasis ( 49 , 53 ) ."
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"DUB3 (official symbol USP17L2) was shown to promote breast cancer invasion and metastasis via stabilizing Snail1 in a CDK4/6 activity-dependent manner ."
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"Expression of Dub3 blocked Snail degradation mediated by the E3 ligases Fbxl14 and Fbxw1 and beta-TRCP 1 [XREF_BIBR]."
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