IndraLab

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Modified USP22 decreases the amount of SIRT1. 1 / 1
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reach
"USP22 knockdown reduced SIRT1 expression in FLT3-ITD AML cells, whereas USP22 overexpression increased SIRT1 levels by increasing protein stability, indicating that USP22 is an important positive regulator of SIRT1 in FLT3-ITD cells."