IndraLab

Statements

CACNA1A inhibits rEag1. 2 / 2
| 2
sparser
"We therefore propose that the eag domain may block the inherent voltage-dependent inactivation of rEag1 channels by directly/indirectly modulating certain gating conformations, such as those involving the S4–S5 linker."
25333352
sparser
"We therefore propose that via its direct interaction with the C-linker/CNBHD, the rEag1 eag domain, but not the hERG1 counterpart, may destabilize or mask an inherent voltage-dependent inactivation of rEag1 channels."
25333352