IndraLab

Statements

Proteasome inhibits USP14. 5 / 5
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"Consequently, we next investigated the effect of proteasome inhibition or specific inhibition of the DUB USP14 on ROS production by macrophages."
31308397
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"Activity probe assays with either the whole 26S proteasome or the 19S regulatory particle showed that the compound blocked the reaction of both USP14 and UCHL5 with haemagglutinin (HA)-tagged ubiquitin vinyl methyl sulfone (VMS)."
26852935
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"Inhibition of USP14 by a small moleculeenhances proteasome activity and decreases misfolded proteins in mammalian cells following proteotoxic stress 11."
29581427
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"By displacing USP14, TRIM11 changes proteasome composition and suppresses both catalytic and non catalytic effects of USP14."
29581427
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"HA-UbVS pretreatment of auranofin could bind the HA tagged UbVS in the purified 26S proteasome, supporting that auranofin inhibits UCHL5 and USP14."
26097878