IndraLab

Statements

SART3 activates USP15. 6 / 6
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"ABHD11-AS1 and SART3 increase the interaction of USP15 with RNA splicing factor PRPF19."
38364571
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"These data further confirming the opposing effect of Tip110 and USP15 on IκBα stability.As we previously alluded to, Tip110 expression promoted the nuclear translocation of USP15 where both are associated (25) and the above observations prompted us to examine whether Tip110 also targeted nuclear IκBα to regulate NF-κB activity."
35530338
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"in which overexpression of SART3 enhanced localization of USP15 to the nucleus."
28088760
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"Our finding demonstrated that ABHD11-AS1 directly and specifically binds to SART3; (ii) Previous studies reported that SART3 interacts with deubiquitinase USP15 and promotes USP15 nuclear localization to regulate RNA alternative splicing."
38364571
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"However, the overexpression of SART3 induced the nuclear localization of USP15, consequently leading to colocalization of USP15 with PRP31."
28088760
reach
"The interaction of ABHD11-AS1 with SART3 promotes USP15 (ubiquitin specific peptidase 15) nuclear localization."
38364571