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GRM2 activates KCNK2. 2 / 2
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"TREK1 activity is rapidly potentiated by activation of the mGluR2 and mGluR4 in CHO cells with little reversibility up to 20 min following drug washout [ 9 ] while the closely related TREK2 channel is[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Stimulation of co-expressed G q -coupled glutamate receptor mGluR1 or the G s -coupled serotonin receptor 5-HT4sR inhibits TREK1 and TREK2 activities, whereas activation of the G i -coupled mGluR2 inc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"