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"Binding of Wnt3a to Frizzled-1 (Fz1) and low-density lipoprotein receptor related protein 5/6 (LRP5/6) facilitates the phosphorylation of LRP5/6, and triggers the interaction of Fz and LRP5/6 complex with dynamic multiprotein complexes."

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"The amino terminal domain of DKK1 plays an inhibitory role on Wnt signalling by binding to the low-density lipoprotein receptor-related protein (LRP5/LRP6) component of the Wnt receptor complex [ xref ]."

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"The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway."

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"These Authors proposed that, upon release from the dense granules of cardiomyocytes, pro-ANP binds to Fz1 and LDLR repeats 1-4, is cleaved by the catalytic domain and releases the mature and biologically active ANP (Fig. xref )."