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Statements

LDLR binds FZD1. 5 / 5
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"The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway."
14739301
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"Binding of Wnt3a to Frizzled-1 (Fz1) and low-density lipoprotein receptor related protein 5/6 (LRP5/6) facilitates the phosphorylation of LRP5/6, and triggers the interaction of Fz and LRP5/6 complex with dynamic multiprotein complexes."
22748080
sparser
"The amino terminal domain of DKK1 plays an inhibitory role on Wnt signalling by binding to the low-density lipoprotein receptor-related protein (LRP5/LRP6) component of the Wnt receptor complex [ xref ]."
23878759
sparser
"These Authors proposed that, upon release from the dense granules of cardiomyocytes, pro-ANP binds to Fz1 and LDLR repeats 1-4, is cleaved by the catalytic domain and releases the mature and biologically active ANP (Fig. xref )."
24524761
sparser
"Proteins from the first class bind directly to the Wnt ligands, whereas the second class of antagonists bind to the low density lipoprotein receptor-related protein (LRP) 5/LRP6 component of the Wnt r[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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