IndraLab

Statements


USP13 activates FASN. 2 / 2
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"USP13 has been shown to upregulate fatty acid synthase (FASN) to promote the proliferation of SCLC cells and Twist-related protein 1 (Twist1) to promote the migration and invasion of breast cancer cells, while it inhibits cell proliferation via downregulation of glycolysis in oral squamous cell carcinoma (47,48)."

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"Mechanistically, USP13 interacts with fatty acid synthase (FASN) and enhances FASN protein stability."