IndraLab

Statements

USP25 decreases the amount of tat. 3 / 3
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"Finally, USP21 inhibits HIV production by specifically downregulating Tat expression by deubiquitinating Tat, causing Tat instability and reducing CyclinT1 mRNA levels [162]."
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"Further investigations revealed that USP21 reduces Tat expression in two ways."
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"Ubiquitin-specific protease 7 (USP7) promotes HIV-1 production by stabilizing Tat protein, whereas our recent study showed that USP21 inhibits HIV-1 replication by downregulating Tat expression."
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