IndraLab

Statements

COPS6 decreases the amount of FASN. 2 / 2
| 2
reach
"The significance of this interaction was demonstrated in that dox-induced CSN6 KD led to increased steady-state-expression of FBXW7β with concurrent decreased expression of FASN (Supplementary Fig. 3b), while CSN6 overexpression reduced FBXW7β and resulted in increased FASN level (Supplementary Fig. 3c)."
37202390
reach
"Consistently, CSN6 decreased the poly-ubiquitination level of FASN in a dose-dependent manner (Fig. 2i)."
37202390