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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP12 activates Ang II-induced cardiac hypertrophy. 2 / 2

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"Moreover , we demonstrate that USP12 aggravate Ang II-induced cardiac hypertrophy by enhancing METTL3 , a methyltransferase which catalyze N 6 - methyladenosine ( m 6 A ) modification on messenger RNA and acts as a harmful factor in pathological cardiac hypertrophy ."

34339675

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eidos

"USP12 deficiency also significantly attenuate the phenotype of Ang II-induced cardiac hypertrophy in vivo ."

34339675

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...