IndraLab

Statements

Protein inhibits IRF3. 3 / 3
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"In addition to encoding multiple proteins that inhibit the interferon regulatory factor 3 ( IRF-3 ) and nuclear factor kappaB ( NF-kappaB ) signaling that would lead to expression of IFN-beta ( Smith et al ., 2018 ) , VACV encodes at least three proteins to directly evade type I IFN ."
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eidos
"We have identified at least ten viral IFN antagonists and all ten proteins inhibit the IRF3 activity ."
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"M protein interacts with TRAF3 and suppresses IRF3 activity ."
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