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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified EIF3F decreases the amount of CLU. 2 / 2

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"Consequently, the overexpression of eIF3f suppressed Akt and ERK signaling and subsequently depleted CLU expression."

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"Overexpression of eIF3f was recently shown to suppress Akt and ERK signaling, increase p53 protein levels and inhibit clusterin protein expression, which promotes cancer cell proliferation and reduces chemosensitivity [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...