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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TNFSF10 activates TNFAIP3. 2 / 2

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"TNFAIP3, that was found to be up-regulated by TRAIL in our study, is an inhibitor of the NFKB pathway [XREF_BIBR] and may thereby promote apoptosis but, on the other hand, it was shown to decrease TNF mediated apoptosis and necrosis [XREF_BIBR], leaving its specific influence unclear."

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"TNFAIP3 and NFkappaBIA, which is found to be up-regulated by TRAIL, are inhibitors of the NF-kappaB pathway [XREF_BIBR, XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...