IndraLab

Statements

TNFSF10 activates TNFAIP3. 3 / 3
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"TRAIL effectively induced apoptotic cell death in HT1080 fibrosarcoma cells by upregulating Arhgdia, Tnfaip3 and Nfkbia by more than two-fold in comparison with the control [27]."
36498988
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"TNFAIP3, that was found to be up-regulated by TRAIL in our study, is an inhibitor of the NFKB pathway [XREF_BIBR] and may thereby promote apoptosis but, on the other hand, it was shown to decrease TNF mediated apoptosis and necrosis [XREF_BIBR], leaving its specific influence unclear."
19077262
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"TNFAIP3 and NFkappaBIA, which is found to be up-regulated by TRAIL, are inhibitors of the NF-kappaB pathway [XREF_BIBR, XREF_BIBR]."
25068924