IndraLab
Statements
reach
"USP37 was shown to directly interact with MYC at the MBIII region and deubiquitinate MYC.112 Although USP37-mediated deubiquitination and stabilization of MYC is independent of either Fbw7 or the phosphorylation of MYC at T58, overexpression of USP37 can block the Fbw7-mediated degradation of MYC."