IndraLab

Statements

Luteolin inhibits RELA. 7 / 7
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"These data together suggested that luteolin treatment inhibited the activation of p65, leading to the loss of cyclin D1, an NF-kB target gene."
21792893
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"Kao et al. found that luteolin decreased the LPS and IFN-gamma-induced nuclear accumulation of p65 and Rel B but not p50, suggesting partial inhibition of NF-kappaB activation in BV-2 microglial cells[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Immunocytochemistry results revealed luteolin can inhibit TNF-alpha-stimulated p65 from nuclear translocation as a transcription factor and thus promoting cell apoptosis."
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"Furthermore, luteolin decreased nuclear accumulation of p65 induced by TBI, indicating attenuation of inflammation."
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"Our report demonstrated that luteolin inhibited the interaction of p65 with CBP and that this event was directly related to the inhibition of NF-kappaB transcriptional activity."
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"also observed that luteolin treated cells showed decreased IkappaBalpha degradation induced by TNF-alpha and significantly decreased NF-kappaB p65 nuclear translocation (Jia et al., 2015)."
29801717
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"Further findings demonstrated that luteolin inhibited the activation of ERK, JNK, p38, and NF-kappaB p65 in the IL-33-stimulated HMC-1.2 cells."
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