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Glucose inhibits MAPK8. 2 / 6
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"Treatment of high glucose cultured ARPE-19 cells with diosmin (10 μg/mL) obviously downregulated the ratios of p-p38/p38 and p-JNK/JNK to 1.0- and 1.1-fold relative to those in normal-glucose vehicle-treated group (Figure 5B,C)."
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"Treatment of HUVECs with media containing high glucose (4.5%) in the presence of 5-HMF (100, 200 and 400 muM) resulted in significant inhibition of high glucose induced oxidative stress and expression of JNK1 and JNK2/3."
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