IndraLab

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Cycloheximide inhibits RIPK1. 2 / 2

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"Using phospho-Ser321 as a marker, we show that the transient phosphorylation of RIPK1 intermediate domain induced by TNFalpha leads to RIPK1 independent apoptosis when NF-kappaB activation is inhibited by cycloheximide."

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"The treatment of TNFα plus the protein synthesis inhibitor cycloheximide (CHX) induces apoptosis independently of RIPK1."

28701375

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IndraLab

Statements

Cycloheximide inhibits RIPK1. 2 / 2

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