IndraLab

Statements

UCHL3 binds FOXM1. 13 / 13
3 | 1 9
biogrid
No evidence text available
31598398
biogrid
No evidence text available
31598398
biogrid
No evidence text available
31598398
sparser
"Collectively, these results suggest that UCHL3 interacts with FOXM1 to promote its deubiquitination, while concurrently inhibiting the activation of the NLRP3 inflammasome, highlighting a critical molecular mechanism underlying EC protection in the context of diabetes-related complications."
40394598
sparser
"UCH-L3-FOXM1 axis could be targeted for the treatment of pancreatic cancer and re-sensitizing gemcitabine resistant cells."
34752952
sparser
"In this study, we hypothesized that UCHL3 binds to FOXM1 to promote its deubiquitination and potentially improve DFU outcomes."
40394598
sparser
"For instance, the progression of pancreatic cancer is promoted by UCHL3-FOXM1 axis [ xref ]."
34016790
sparser
"UCHL3 binds to FOXM1 and promotes FOXM1 deubiquitination while inhibiting NLRP3 inflammasome activation."
40394598
sparser
"To further investigate the interaction between UCHL3 and FOXM1, immunoprecipitation assays were performed."
40394598
sparser
"UCHL3 interacts with FOXM1 and enhances FOXM1 stabilization as well as reduces FOXM1 turnover via deubiquitination manner, thereby promoting growth, migration, invasion and resistance to gemcitabine in PC [ xref ]."
40691601
reach
"Co-immunoprecipitation (co-IP) and in vitro deubiquitination assays were performed to investigate the interactions between UCHL3 and FOXM1."
31598398
sparser
"Co-immunoprecipitation (co-IP) and in vitro deubiquitination assays were performed to investigate the interactions between UCHL3 and FOXM1."
31598398
sparser
"High UCHL3 expression was positively associated with FOXM1 expression level in pancreatic cancer patient samples."
31598398