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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53 bound to TP53BP1 activates TP53. 3 / 3

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"53BP1 binds to p53 and enhances p53 mediated transcriptional activation."

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"Because 53BP1 binds to p53 and enhances p53 mediated transcriptional activity, 53BP1 mediated regulation of mitochondrial function might be required for p53 to function properly."

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"The mechanistic principles by which p53 interacts with 53BP1 and promotes accumulation of p53 at the sites of DNA damage may help in identification of new diagnostic markers and targets within cancer-critical p53 mediated signaling pathways."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

TP53 bound to TP53BP1 activates TP53. 3 / 3

Our Sources:

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