
IndraLab
Statements
Eplerenone inhibits NLRP3. 1 / 1
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1
reach
"In vitro, exposure of podocytes to Aldo enhanced NLRP3, caspase-1, and IL-18 expressions in dose- and time dependent manners, indicating an activation of NLRP3 inflammasome, which was significantly blocked by the mineralocorticoid receptor antagonist eplerenone or the antioxidant N -acetylcysteine."