IndraLab

Statements

USP6 activates cell population proliferation. 7 / 7
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"The overactive USP6 protein promotes cell survival, proliferation, and resistance to apoptosis, all of which are significant features of cancer growth."
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"In human CRC cell lines, USP6 knockdown reduced cell proliferation, caused G0/G1 cell cycle arrest, and stopped cells from becoming tumorigenic in nude mice."
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"USP6 depletion could inhibit cell proliferation and migration, reduce the colony number and induce apoptosis, which could be reversed by GOLPH3 overexpression in HT29 and HCT116 cells ( Fig. 3 F–I)."
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"Tre2 (USP6NL) promotes colorectal cancer cell proliferation via Wnt and beta-catenin pathway."
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"The identification of the USP6 gene as a recurrent and specific finding in these studies has led to the conclusion that NF is a form of neoplastic proliferation [13–15]."
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"Therefore, the upregulation of USP6 expression can enhance proliferation and hinder apoptosis by means of the GOLPH3 protein in COAD.USP6 rearrangements were initially discovered in a primary aneurysm[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"USP6 silencing suppressed the migration and proliferation in primary Schwann cells."
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