IndraLab

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USP53 inhibits NFASC. 4 / 4
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"Here, we can guess that USP53 may inhibit the NF‐κB pathway by inhibiting the degradation of IκBα."

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"We described a new mechanism by which USP53 inhibits ccRCC survival via the downregulation of the NF‐κB signaling pathway."

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"USP53 (Ubiquitin specific peptidase 53) inhibits the initiation and progression of renal cell carcinoma by inhibiting activation of the nuclear factor κB (NF‐κB) pathway; it promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through FKBP51‐AKT1 signaling [52, 53]."

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"Furthermore, USP53 inhibited the progression of clear cell renal cell carcinoma by suppressing the nuclear factor κB (NF‐κB) pathway [9]."