IndraLab

Statements

Lipopolysaccharide inhibits IRF7. 3 / 3
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eidos
"Thus , the present finding that IRF7 was upregulated by LPS and downregulated in response to AST treatment may suggest that of AST protects against ALI ."
32969837
reach
"The data showed that LPS stimulation significantly activated the IFN-I signalling pathway, and knockdown of MEF2D markedly inhibited the elevation of IRF7, IFNA1, MX2, IFIT1, IFI27, ISG15, RSAD2, ZBP1 and DDX58 (XREF_FIG)."
34234510
reach
"The critical importance of IRF mediated signaling to the neuroprotective process is shown clearly by the fact that mice lacking IRF3 or IRF7 fail to be protected or exhibit much reduced protection when treated with CpG, LPS or brief ischemia."
21653850