IndraLab

Statements

COPS5 activates cell differentiation. 6 / 7
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"We found that increased expression of JAB1 promoted odontogenic differentiation of DPSCs via Wnt and beta-catenin signaling."
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"Interestingly, JAB1 activated CPNE1 related neuronal differentiation."
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"Moreover, the knockdown of Jab1 attenuated 5-HT 6 R agonist induced-Runx2 suppression as well as osteoblast differentiation as evidenced by ALP staining (XREF_FIG) and activity (F) and differentiation markers, ALP, OCN, and bone sialoprotein (BSP) (XREF_FIG)."
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"Interestingly, JAB1 activated CPNE1 related neuronal differentiation."
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"Collectively, our findings suggest that JAB1 activates the neuronal differentiation ability of CPNE1 through the binding of C2A domain in CPNE1 with MPN domain in JAB1."
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"JAB1 accelerates odontogenic differentiation of dental pulp stem cells."
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