IndraLab

Statements

THBS1 binds CD4. 3 / 3
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reach
"Additionally, TSP-1 binds CD4 to block HIV entry into target cells."
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sparser
"Additionally, TSP-1 binds CD4 to block HIV entry into target cells ( xref )."
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reach
"Given the lack of empirical data and the complexity of the signaling processes, we set out here to interrogate potential mechanisms for the inhibition of VEGF and VEGFR2 signaling to ERK1/2 and calcium by TSP1 and CD4 interaction utilizing a detailed rule based model of VEGF signaling to ERK1/2 and calcium incorporating VEGFR2, the co-receptor NRP1, and the detailed dynamics of the receptors."
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