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USP8 inhibits autophagy. 2 / 2

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"We show here that UBPY silencing also activates autophagy in absence of CCCP treatment, which strongly suggests that UBPY is not connected exclusively to mitophagy."

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"USP8 inhibitor , DUB-IN-1 , treatment could inhibit esophageal squamous cell carcinoma cell growth and induce G2 / M cell cycle arrest , apoptosis , and autophagy by DNA damage-induced p53 activation ."

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USP8 inhibits autophagy. 2 / 2

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