IndraLab

Statements

USP43 activates Neoplasms. 4 / 4
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"In vivo xenograft tumors, silencing USP43 slowed tumor growth and enhanced cisplatin sensitivity."
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"Knockdown of USP43 inhibited tumor growth and enhanced cisplatin sensitivity of EOCin vivo.."
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"Thus, we concluded that knockdown of USP43 inhibited tumor growth and enhanced cisplatin sensitivity of EOC in vivo."
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"These findings suggest that the two functions of USP43 operate in coordination to maintain c-Myc as an oncoprotein and promote tumor progression (Fig. 8)."
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