IndraLab

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SERPINE1 activates CYLD. 2 / 2

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"CYLD knockdown by using siRNA- CYLD increased PAI-1 mRNA expression in WT MEF cells, whereas overexpression of WT CYLD attenuated PAI-1 mRNA expression in Cyld −/− MEF cells ( Figure S5 A)."

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reach

"Since PAI-1 inhibits plasminogen production and fibrinolysis, the indirect inhibition of PAI-1 by CYLD in combination with reduced lung hemorrhage and increased PAI-1 production of Cyld -/- mice indicate that CYLD caused augmented fibrinolysis."

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IndraLab

Statements

SERPINE1 activates CYLD. 2 / 2

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