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OTUD7B activates MAP3K14. 1 / 1

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"TRAF3 and TRAF2 could recruit cIAP1/2 to catalyze K48‐linked ubiquitination and subsequent degradation of NIK.11, 12 NLRP12 or OTUD7B stabilizes TRAF3 and subsequently accelerates NIK degradation.13, 14 Lastly, IKKα and TBK1 may induce NIK phosphorylation‐dependent degradation.15, 16 In contrast to NIK, little is known about how the downstream subunit p100/p52 is regulated."

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IndraLab

Statements

OTUD7B activates MAP3K14. 1 / 1

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