IndraLab

Statements

PRPF8 binds PRPF3. 10 / 10
6 | 2 2
biogrid
No evidence text available
28515276
reach
"The interaction of PRP31 or PRP3 and the U5 snRNP component PRP8 is reported to be regulated by the ubiquitination and deubiquitination status of PRP31 and PRP3, which is required for efficient RNA sp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31330151
biogrid
No evidence text available
35271311
biogrid
No evidence text available
34144037
reach
"The SNRNP200, PRPF8, PRPF3, and PRPF31 gene products are all triple-snRNP components, 15,31 and PAP1 binds PRPF3 to negatively regulate splicing, 32,49 suggesting a common mechanism for pathogenesis."
19878916
sparser
"It is interesting to note that the interaction of PRPF8 with ubiquitinated PRPF3 is regulated by the deubiquitinating enzyme USP4, and that loss of USP4 prevents the correct splicing of mRNAs including those for α-tubulin xref ."
26167768
biogrid
No evidence text available
22939629
biogrid
No evidence text available
20595234
sparser
"As the second and third PE targets, we chose PRPF3 and PRPF8 associated with autosomal dominant (ad) forms of retinitis pigmentosa (RP) [ xref , xref ]."
39795970
biogrid
No evidence text available
26344197