IndraLab

Statements

PRPF8 binds PRPF3. 6 / 6
3 | 1 2
biogrid
No evidence text available
20595234
sparser
"It is interesting to note that the interaction of PRPF8 with ubiquitinated PRPF3 is regulated by the deubiquitinating enzyme USP4, and that loss of USP4 prevents the correct splicing of mRNAs including those for α-tubulin xref ."
26167768
biogrid
No evidence text available
26344197
biogrid
No evidence text available
22939629
sparser
"We also found that PRPF19 regulates MDM4 splicing by promoting the physical interaction of other splicing factors, PRPF3 and PRPF8, which are key components of the core spliceosome, U4/U6."
34144037
reach
"The SNRNP200, PRPF8, PRPF3, and PRPF31 gene products are all triple-snRNP components, 15,31 and PAP1 binds PRPF3 to negatively regulate splicing, 32,49 suggesting a common mechanism for pathogenesis."
19878916