IndraLab

Statements


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"Dysregulated STAMBP expression induces oncogenic features through altered ubiquitin signaling of substrate proteins by directly binding with the C-terminal JAMM domain of STAMBP, which could facilitate cellular transformation and tumor development."

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"The AMSH-family JAMM domains bind two zinc ions, one a structural zinc ion bound to the conserved JAMM core, and the second a catalytic zinc ion bound by residues of Ins-2."