IndraLab

Statements

COPS5 inhibits JNK. 2 / 2
| 2
reach
"MIF can also interact with intracellular binding proteins, such as JUN-activation domain-binding protein 1 (JAB1), through which it can block the activity of JNK pathway and its target transcription factor AP-1 (128)."
34956045
reach
"MIF signals through at least three cell surface receptors, including the CD74/44 complex, CXCR2 and CXCR4 16-18 but also signals by intracellular interaction with the JAB-1 thus inhibiting JNK activation and p27 Kip1 -dependent cell-cycle regulation."
33447370