IndraLab

Statements

USP7 deubiquitinates KDM1A. 7 / 8
1 | 7
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"Furthermore, USP7 inhibits LSD1 ubiquitination and stabilizes LSD1in glioma [XREF_BIBR]."
30150556
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"USP7 inhibited LSD1 ubiquitination and stabilized LSD1 in A172 and T98G cells."
27632941
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"From a functional standpoint, the researchers further showed that the dimethylation of LSD1 at arginine 838 (R838) by CARM1 facilitates the binding of LSD1 to USP7, which, in turn, deubiquitinates and stabilizes LSD1."
39394462
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"USP7 deubiquitinates LSD1 and promotes cell proliferation and invasion of glioblastoma cells, suggesting that USP7 is a prognostic marker and therapeutic target for gliomas and other neuronal disorders (38)."
38952059
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"Next, methylated LSD1 would bind to the deubiquitinating enzyme USP7, which leads to the deubiquitylation of LSD1."
38572094
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"USP7 deubiquitinates histone demethylases PHF8 and LSD1 as well as the histone methyltransferase MLL5 ( Wang et al., 2016 ; Yi et al., 2016 ; Ding et al., 2015 )."
32603670
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"Ubiquitin-specific peptidase 7 (USP7) and OTU deubiquitinase 7B (OTUD7B) mediate the deubiquitylation and stability of LSD1, which is crucial for breast cancer invasion and metastasis [ 13 , 14 ]."
37328395