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ATXN3 deubiquitinates KLF4. 3 / 3
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"Additionally, ATXN3 was highly expressed in breast cancer and it promotes tumor tissue metastasis by deubiquitinating and stabilizing KLF4 [46]."

"We screened a library of 65 deubiquitinating enzymes and identified ATXN3 as a deubiquitinating enzyme of KLF4."

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"ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4."