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OTUD4 activates IRF3. 2 / 2

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"Knockout or knockdown of OTUD4 impairs RNA virus triggered activation of IRF3 and NF-kappaB, expression of their downstream target genes, and potentiates VSV replication in vitro and in vivo."

30410068

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"Additionally, the knockout of OTUD4 impairs RNA virus-triggered activation of IRF3 and NF-kB and the expression of their downstream target genes, and potentiates VSV replication in vitro and in vivo (66) ."

34707613

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OTUD4 activates IRF3. 2 / 2

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