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"In fact, it was shown for several bacteriocins that the double glycine SPs can be successfully replaced by Sec-dependent SPs (McCormick et al., 1996; Martín et al., 2007; Borrero et al., 2011; Back et al., 2016) and recently a fusion of the SP of lactococcal protein Usp45 and GarQ allowed recombinant GarQ production by L. lactis (Feito et al., 2023)."