IndraLab

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BAP1 decreases the amount of H2AK119ub1. 2 / 2
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"Moreover, the reintroduction of wild-type BAP1 into 769-P cells (BAP1 mutant cells) downregulates H2AK119ub1 levels in renal cancer cells ( Pena-Llopis et al., 2012 )."

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"Previous studies showed that BAP1 knockdown led to increased global H2AK119ub1 levels in UM and renal carcinoma cell lines ( Landreville et al., 2012; Pena-Llopis et al., 2012 )."