IndraLab

Statements

EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor inhibits MYD88. 3 / 3
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reach
"In addition, association of B. burgdorferi with actin related protein (Arp2/3) complexes, which facilitate actin rearrangements during phagocytosis, was similarly reduced in MyD88 -/- BMDMs and BMDMs treated with a PI3K inhibitor."
19542460
reach
"Additionally, association of B. burgdorferi with actin related protein (Arp2/3) complexes, which facilitate actin rearrangements during phagocytosis, was similarly reduced in MyD88 (-/-) BMDMs and in BMDMs treated with a PI3K inhibitor."
19542460
reach
"We show that both MyD88 -/- BMDMs and WT BMDMs treated with a PI3K inhibitor failed to recruit Arp3 to sites of B. burgdorferi, suggesting a potential role of MyD88 and PI3K for initiating actin polymerization (XREF_FIG)."
19542460