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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

CCND1 binds CD44, CDK4, and PLK1. 1 / 1

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"From the analysis, NSC765600 and NSC765691- CCND1 , CDK4 , PLK1 , and CD44 complexes displayed the highest binding energies of −9.3, −8.3, −7.4 and −7.0 kcal/mol and (−9.6, −8.0, −7.7 and −7.3 kcal/mol, respectively ( xref and xref and accompanying tables), as compared to the standard inhibitors’ results, which were −7.5, −7.6 and −7.9 kcal/mol for fascaplysin, ribociclib, and volasertib- CCND1 , CDK4 , and PLK1, respectively ( xref , accompanying table)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...