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USP15 increases the amount of CD44v6. 3 / 3

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"USP15 and PRPF19 mediate the effect of ABHD11-AS1 on CD44 alternative splicing to increase the expression of CD44v6."

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"Furthermore, silence of USP15 or PRPF19 in ABHD11-AS1-overexpressing HCC15 cells also reduced CD44, CD44v6, total and active β-catenin levels, and these effects were partially reversed by CD44v6 overexpression (Fig. 8d)."

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"In addition, knockdown of USP15 or PRPF19 drastically decreased CD44, CD44v6, total and active β-catenin levels in A549 cells."

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IndraLab

Statements

USP15 increases the amount of CD44v6. 3 / 3

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