IndraLab

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USP19 inhibits SLC7A11. 2 / 2

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"Mechanistically, USP19 inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing its K63-linked ubiquitin chains."

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"Notably, USP19 overexpression reduces ferroptosis and IRI in a SLC7A11-dependent manner in mice."

39574305

INDRA sources:

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IndraLab

Statements

USP19 inhibits SLC7A11. 2 / 2

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