IndraLab

Statements


USP8 activates CCL5. 2 / 2
| 2

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"CCL5 WT promoter activity was increased by approximately sixfold in USP8-depleted cells, consistent with the increase in CCL5 mRNA levels (Fig. 3 B)."

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"Luciferase assays using the CCL5 WT promoter showed that additional depletion of either TAK1, TAB2/3, or all the IKK subunits (α, β, and γ) with USP8 at least partially abolished CCL5 promoter activation (Fig. 3 E)."