IndraLab

Statements

Modified USP9X leads to the deubiquitination of SMAD4. 3 / 3

| 3

reach

"Strikingly, overexpression of wild-type FAM, but not of the catalytically inactive FAM mutant, inhibited Smad4 monoubiquitination in vivo."

19135894

➶

reach

"Loss of USP9X therefore prevents deubiquitination of SMAD4, enhancing tumour progression."

24292195

➶

reach

"Overexpression of FAM also inhibits monoubiquitination of endogenous Smad4."

19135894

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Modified USP9X leads to the deubiquitination of SMAD4. 3 / 3

INDRA sources:

Databases

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