IndraLab

Statements


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"These data indicate that USP4 interacts with SOX9 and stabilizes its function via proteasome pathway."

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"EVO inhibites CRC stemness via affecting USP4-SOX9 axis."

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"These findings suggest that EVO decreases SOX9 level by inducing USP4 degradation, thus further inhibits CRC cell stemness by impairing USP4-SOX9 axis."

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"Next, we observed physical interactions between USP4 and SOX9 by immunoprecipitation assay (Fig.  xref D)."