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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

IL6 activates CYLD. 2 / 2

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"In addition to pathogen control, the production of listericidal ROS and NO as well as the cytokines IL-6 and IL-12 were significantly increased in IFN-gamma-treated Lm infected Cyld -/- BMDM."

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"In good agreement, we also observed that increased IL-6 production of Cyld -/- mice upon high-dose Lm infection correlated with an augmented recruitment of neutrophils causing an improved control of Lm in the liver."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...