IndraLab

Statements


State inhibits KCNH2. 3 / 3
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"State dependent block of HERG potassium channels by R-roscovitine : implications for cancer therapy."

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"State dependent barium block of wild-type and inactivation deficient HERG channels in Xenopus oocytes."

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"State dependent inhibition of hERG channel currents and slow kinetics for recovery from block suggest that many drugs bind within the inner cavity of the channel and are trapped by closure of the activation gate upon repolarization."